The North American Free Trade Agreement (NAFTA), signed by Prime Minister Brian Mulroney, Mexican President Carlos Salinas and U.S. President George H.W. Bush, came into force on January 1, 1994. NAFTA has created economic growth and a rising standard of living for the people of the three member countries. By strengthening trade and investment rules and procedures across the continent, Nafta has proven to be a solid foundation for building Canada`s prosperity. NAFTA replaced Canada-U.S. Free Trade Agreement (CUFTA). Negotiations on CUFTA began in 1986 and the agreement entered into force on 1 January 1989. The two nations agreed on a landmark agreement that put Canada and the United States at the forefront of trade liberalization. For more information, visit the Canada-U.S.

Free Trade Agreement information page. In addition to its work with the WTO, the United States has concluded trade agreements with 20 countries that cover a number of issues, ranging from tariffs on goods and access to the agricultural market to intellectual property and the environment. For the FDA, the specific themes are chapters of agreements on regulatory issues such as SPS measures, OBTs and good regulatory practices – as well as sector chapters on cosmetics, medical devices and drugs, if any. The FDA helps develop negotiation proposals in the United States and the FDA is actively involved in trade negotiations with U.S. trading partners. If the Trans-Pacific Partnership of Origin (TPP) were to enter into force, existing agreements, such as NAFTA, would be reduced to provisions that do not conflict with the TPP or require greater trade liberalization than the TPP. [155] However, only Canada and Mexico would have the prospect of becoming members of the TPP after U.S. President Donald Trump withdrew the United States from the agreement in January 2017. In May 2017, the remaining 11 members of the TPP, including Canada and Mexico, agreed to pursue a revised version of the trade agreement without U.S. participation. [156] The USMCA will have an impact on the way Member States negotiate future free trade agreements. Section 32.10 requires USMCA countries to notify USMCA members three months in advance if they plan to enter into free trade negotiations with non-market economies.